6-Chloro-3-methyl-pyridine-2-carboxylic acid

6-Chloro-3-methyl-pyridine-2-carboxylic acid - Names and Identifiers

Name	2-Pyridinecarboxylic acid, 6-chloro-3-methyl-
Synonyms	6-chloro-3-methylpyridine-2-carboxylicaci 6-Chloro-3-Methylpyridine-2-carboxylic Acid 6-Chloro-3-methyl-pyridine-2-carboxylic acid 2-Pyridinecarboxylic acid, 6-chloro-3-methyl-
CAS	1201924-32-4
InChI	InChI=1S/C7H6ClNO2/c1-4-2-3-5(8)9-6(4)7(10)11/h2-3H,1H3,(H,10,11)

6-Chloro-3-methyl-pyridine-2-carboxylic acid - Physico-chemical Properties

Molecular Formula	C7H6ClNO2
Molar Mass	171.58
Density	1.390±0.06 g/cm3(Predicted)
Boling Point	333.7±37.0 °C(Predicted)
pKa	2.93±0.32(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Sensitive	Irritant
MDL	MFCD16249840

6-Chloro-3-methyl-pyridine-2-carboxylic acid - Risk and Safety

WGK Germany

6-Chloro-3-methyl-pyridine-2-carboxylic acid - Introduction

6-Chloro-3-methylpyridine-2-carboxylic acid is an organic compound whose chemical formula is C8H8ClNO2.

Nature:
6-Chloro-3-methylpyridine-2-carboxylic acid is a colorless to pale yellow solid with a special odor. It is insoluble in water, but can be dissolved in some organic solvents, such as ethanol and dimethylformamide. It is stable at room temperature, but may decompose under high temperature and light.

Use:
6-Chloro-3-methylpyridine-2-carboxylic acid is commonly used as an intermediate in organic synthesis. It can be used to synthesize a series of drugs, pesticides and dyes. In addition, it can also be used as an ion-selective electrode for aluminum, manganese and nickel.

Preparation Method:
The method for preparing 6-chloro-3-methylpyridine-2-carboxylic acid is usually by dissolving 3-methylpyridine in hydrogen chloride acid, and adding sulfoxide and tetraacetyl methyl ammonium. After the reaction, it is neutralized with a base, and then the product is obtained by filtration and crystallization.

Safety Information:
6-Chloro-3-methylpyridine-2-carboxylic acid has low toxicity under general use conditions. However, as an organic compound, it can still cause irritation and skin irritation to the human body. Avoid inhalation, contact with skin and eyes during use and storage. When handling this compound, it is recommended to use appropriate personal protective equipment, such as laboratory gloves and goggles. Observe local regulations when disposing of waste. In the event of an accident or accidental ingestion, medical help should be sought immediately.

Last Update：2024-04-09 20:52:54